Quantitative cross-linking/mass spectrometry using isotope-labelled cross-linkers
نویسندگان
چکیده
منابع مشابه
Quantitative cross-linking/mass spectrometry using isotope-labelled cross-linkers☆
UNLABELLED Dynamic proteins and multi-protein complexes govern most biological processes. Cross-linking/mass spectrometry (CLMS) is increasingly successful in providing residue-resolution data on static proteinaceous structures. Here we investigate the technical feasibility of recording dynamic processes using isotope-labelling for quantitation. We cross-linked human serum albumin (HSA) with th...
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ژورنال
عنوان ژورنال: Journal of Proteomics
سال: 2013
ISSN: 1874-3919
DOI: 10.1016/j.jprot.2013.03.005